| Normoxia | Hypoxia | Normoxia switch after hypoxia | |||
---|---|---|---|---|---|---|
 | Placebo | Naloxone | Placebo | Naloxone | Placebo | Naloxone |
Power (watt) | 296 ± 48 | 292 ± 52 | 182 ± 36* | 184 ± 34* | 282 ± 51 | 291 ± 49 |
Time (min) | 22.5 ± 2.6 | 22.3 ± 2.4 | 22.0 ± 3.8 | 22.4 ± 3.7 | 27.1 ± 4.2 | 27.6 ± 3.9 |
HR (/min) | 184 ± 5 | 181 ± 7 | 169 ± 7* | 168 ± 7* | 173 ± 5 | 170 ± 6 |
Lactate (mM) | 11.3 ± 3.7 | 10.5 ± 2.4 | 10.4 ± 2.9 | 10.3 ± 3.7 | 11.3 ± 3.0 | 10.9 ± 5.1 |
RPE global (a.u.) | 9.7 ± 0.5 | 9.6 ± 0.5 | 9.4 ± 0.7 | 9.7 ± 0.5 | 9.3 ± 0.9 | 9.4 ± 0.5 |
RPE resp (a.u.) | 9.5 ± 0.7 | 9.4 ± 0.9 | 9.5 ± 0.6 | 9.5 ± 0.7 | 9.0 ± 1.1 | 8.9 ± 0.4 |
RPE legs (a.u.) | 9.9 ± 0.3 | 9.7 ± 0.7 | 9.6 ± 0.5 | 9.8 ± 0.4 | 10.0 ± 0.0 | 10.0 ± 0.0 |
SaO2 (%) | 91.7 ± 4.1 | 93.3 ± 6.4 | 67.5 ± 8.9* | 63.6 ± 8.8* | 90.55± | 95.70± |
PETCO2 (kPa) | 4.44 ± 0.70 | 4.56 ± 0.48 | 3.50 ± 0.18* | 3.49 ± 0.26* | 4.48 ± 0.32 | 4.42 ± 0.40 |
V'O2 (L/min) | 3.77 ± 0.8 | 3.85 ± 0.76 | 2.39 ± 0.40* | 2.39 ± 0.40* | 3.53 ± 0.71 | 3.64 ± 0.63 |
V'CO2(L/min) | 4.92 ± 1.1 | 4.86 ± 0.80 | 3.19 ± 0.53* | 3.30 ± 0.57* | 3.86 ± 0.78 | 4.05 ± 0.85 |
V'E (L/min) | 150 ± 33 | 146 ± 21 | 128 ± 20* | 133 ± 24* | 123 ± 21 | 132 ± 28 |
V'A (L/min) | 159 ± 43 | 154 ± 27 | 133 ± 26* | 137 ± 37* | 126 ± 27 | 138 ± 37 |
Vt (L) | 2.98 ± 0.39 | 3.16 ± 0.41 | 2.89 ± 0.51 | 2.97 ± 0.72 | 2.91 ± 0.45 | 3.09± |
RR (/min) | 50 ± 8 | 47 ± 7 | 45 ± 7 | 44 ± 7 | 42 ± 6 | 43 ± 5 |
MEFR (L/sec) | 5.1 ± 1.2 | 5.0 ± 0.8 | 4.2 ± 0.7 | 4.3 ± 0.9 | 4.1 ± 0.8 | 4.4 ± 1.0 |