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Table 7 Time course of hypoxic response

From: Skeletal muscle energy metabolism in environmental hypoxia: climbing towards consensus

Duration Glycolysis β-oxidation TCA cycle function Oxidative phosphorylation Mitochondrial density
  = = = = =
Short 0% 50% 50% 0% 75% 25% 0% 50% 50% 0% 50% 50% 0% 100% 0%
Medium 33% 50% 17% 0% 67% 33% 0% 86% 14% 0% 0% 100% 0% 60% 40%
Long 0% 50% 50% 0% 50% 50% 0% 50% 50% 0% 0% 100% 0% 33% 67%
  1. The percentage of hypoxic settings in which biomarkers report a significant decrease (), a significant increase () or unchanged/unclear results (=) in human m. vastus lateralis, following short- (0–14 d), medium- (15–42 d) or long- (43–90 d) term exposure to an environmental p(O2) <15 kPa.