Author and year | Type of outcome variable | Population | PiO 2 of exposure (calculated by PiO 2   = (Pb-47) × FiO 2 [4]) (mmHg) | Duration of exposure (h:min) | Randomised (Y, N) | Washout period between trials (days:h) | |
---|---|---|---|---|---|---|---|
NH HH | |||||||
Basualto-Alarcon 2012 | Ventilatory and cardiovascular + exercise | 7 men | 3,000 mc | 3,000 mc | 00:15 builda, 00:10 | N | 7 |
Degache 2012 | Postural stability | 12 men | 118 and 102 | 121 and 103 | 00:20–25 builda, 00:30b | Nil stated | <00:24 |
Hemmingsson 2009 | Exhaled NO | 6 men, 2 women | 103 and 81 | 99 and 75 | 00:10 at each altitude | Y | <00:12 |
Loeppky 2005 | Fluid balance | 9 men | 81 | 80 | 00:05 builda 10:00 | Y | 7 |
Loeppky 1997* | Ventilatory and cardiovascular | 9 men | 81 | 80 | 00:05 builda 10:00 | Y | 7 |
Miyagawa 2010 | Ventilatory, cardiovascular and sweat + exercise | 7 men | 93 | 97 | 00:30 builda only for HH 01:40 | Y | >6 |
Naughton 1995 | Haematological + exercise | 9 subjects with chronic airflow limitation (CAL) with 6 controls | 1,829 and 2,438 mc | 117 and 108 | 00:12 builda included 00:52:00 | Y | 00:02 |
Roach 1996 | AMS and cardiovascular | 9 men | 4,564Â mc | 80 | 09:00 | Y | 7 |
Savourey 2003 | Ventilatory and cardiovascular | 18 men | 4,500Â mc | 4,500Â mc | 00:10 builda, 00:30 | Y | 7 |
Savourey 2007 | Ventilatory and cardiovascular | 17 men, 1 woman | 4,500Â mc | 4,500Â mc | 00:10 builda, 00:30 | Y | 14 |
Self 2011 | AMS and cardiovascular | 17 men and 3 women | 7,620Â mc | 7,620Â mc | 00:05 | N | <00:24 |
Tucker 1983 | Mixed | 11 men | 82 | 80 | 00:15 builda included 02:20 | N | Several weeks |
Faiss 2013 | Exhaled NO, ventilatory and cardiovascular + exercise | 10 men | 99 | 101 | 24:00:00 | Y | 23 |