Keratinocytes at the uppermost layer of epidermis might act as sensors of atmospheric pressure change

Table 1 Physiological factors produced by and released from epidermal keratinocytes

	References
Factors influencing the nervous system
ATP	[14]
Prostaglandin E2	[16]
Glutamate	[8]
Dopamine	[8]
Factor influencing the cardiovascular system
Nitric oxide (NO)	[17]
Factors influencing the endocrine and immune systems
Proopiomelanocortin (POMC)	[18]
Corticotropin releasing hormone (CRH)	[18]
Cortisol	[19]
IL-1α	[20]
TNF-α	[20]
IL-6	[20]

ISSN: 2046-7648