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Table 4 Cardiovascular variables

From: The physiological effects of hypobaric hypoxia versus normobaric hypoxia: a systematic review of crossover trials

Outcomes Author and year Duration of exposure (h:min) Hypobaric hypoxia result [mean (SD)] Normobaric hypoxia result [mean (SD)] Difference (HH − NH) P value Direction of difference NH compared to HH
Hypoxic cardiac response (HCR) bpm %−1        
  Savourey 2007 00:10 builda, 00:05 −0.61 −0.63 0.02 >0.05 NS
Savourey 2007 00:10 builda, 00:30 −0.52 −0.79 0.27 >0.05 NS
LF/HF%        
  Basualto-Alarcon 2012 00:15 builda, 00:10 acclimatisation 1.96 (2.6) 1.28 (0.92) 0.68 <0.05 HH > NH
HR        
  Self 2011 00:01 104.9 (14.3) 96.6 (14.6) 8.3 <0.05 HH > NH
Self 2011 00:04 - - - >0.05 NS
Basualto-Alarcon 2012 00:15 builda, 00:05 acclimatisation 61 (9) 62 (6) −1 - -
Basualto-Alarcon 2012 00:15 builda, 00:10 acclimatisation 129 (23) 134 (16) −5 <0.05 NH > HH
Savourey 2007 00:10 builda, 00:05 70.32 (9.91) 69.62 (9.95)   >0.05 NS
Savourey 2003 00:10 builda, 00:30 - - - <0.05 HH > NH
Savourey 2007 00:10 builda, 00:30 69.50 (12.07) 70.67 (12.07) - >0.05 NS
Faiss 2013 01:00 62 (8) 63 (10) −1 >0.05 NS
Miyagawa 2010 01:05 144 137 - >0.05 NS
Miyagawa 2010 01:10 150 146 - >0.05 NS
Miyagawa 2010 01:40 166 164 - >0.05 NS
Tucker 1983a 02:20 including 00:15 builda 10.4 3.6 6.8 - HH > NH
Faiss 2013 08:00 68 (13) 69 (13) −1 >0.05 NS
Faiss 2013 16:00 61 (10) 66 (7) −5 >0.05 NS
Faiss 2013 24:00 65 (9) 71 (10) −6 >0.05 NS
Stroke volume        
  Miyagawa 2010 01:05 105 107 −2 >0.05 NS
Miyagawa 2010 01:10 113 126 −13 >0.05 NS
Miyagawa 2010 01:40 116 124 −8 >0.05 NS
Cardiac output        
  Miyagawa 2010 01:05 15.3 14.7   >0.05 NS
Miyagawa 2010 01:10 17.1 18.2   >0.05 NS
Miyagawa 2010 01:40 19.4 20.1   >0.05 NS
Mean BP        
  Miyagawa 2010 01:05 112 107   >0.05 NS
Miyagawa 2010 01:10 108 107   >0.05 NS
Miyagawa 2010 01:40 100 99   >0.05 NS
BP systolic (Torr)        
  Faiss 2013 01:00 124 (9) 129 (13) −5 >0.05 NS
Tucker 1983b 02:20 including 00:15 builda −1 5 −6   NH > HH
Faiss 2013 08:00 124 (9) 123 (7) 1 >0.05 NS
Faiss 2013 16:00 121 (9) 118 (9) 3 >0.05 NS
Faiss 2013 24:00:00 131 (10) 129 (9) 2 >0.05 NS
  1. This table lists all the values of the measured variables that relate to the cardiovascular system.
  2. NS insignificant.
  3. aWhen the subjects entered the chamber, the environmental conditions were that of normal sea level but then were gradually made more hypoxic over the specified amount of time until the target hypoxic dose was reached.
  4. bDifference from controls.