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Table 4 Cardiovascular variables

From: The physiological effects of hypobaric hypoxia versus normobaric hypoxia: a systematic review of crossover trials

Outcomes

Author and year

Duration of exposure (h:min)

Hypobaric hypoxia result [mean (SD)]

Normobaric hypoxia result [mean (SD)]

Difference (HH − NH)

P value

Direction of difference NH compared to HH

Hypoxic cardiac response (HCR) bpm %−1

       
 

Savourey 2007

00:10 builda, 00:05

−0.61

−0.63

0.02

>0.05

NS

Savourey 2007

00:10 builda, 00:30

−0.52

−0.79

0.27

>0.05

NS

LF/HF%

       
 

Basualto-Alarcon 2012

00:15 builda, 00:10 acclimatisation

1.96 (2.6)

1.28 (0.92)

0.68

<0.05

HH > NH

HR

       
 

Self 2011

00:01

104.9 (14.3)

96.6 (14.6)

8.3

<0.05

HH > NH

Self 2011

00:04

-

-

-

>0.05

NS

Basualto-Alarcon 2012

00:15 builda, 00:05 acclimatisation

61 (9)

62 (6)

−1

-

-

Basualto-Alarcon 2012

00:15 builda, 00:10 acclimatisation

129 (23)

134 (16)

−5

<0.05

NH > HH

Savourey 2007

00:10 builda, 00:05

70.32 (9.91)

69.62 (9.95)

 

>0.05

NS

Savourey 2003

00:10 builda, 00:30

-

-

-

<0.05

HH > NH

Savourey 2007

00:10 builda, 00:30

69.50 (12.07)

70.67 (12.07)

-

>0.05

NS

Faiss 2013

01:00

62 (8)

63 (10)

−1

>0.05

NS

Miyagawa 2010

01:05

144

137

-

>0.05

NS

Miyagawa 2010

01:10

150

146

-

>0.05

NS

Miyagawa 2010

01:40

166

164

-

>0.05

NS

Tucker 1983a

02:20 including 00:15 builda

10.4

3.6

6.8

-

HH > NH

Faiss 2013

08:00

68 (13)

69 (13)

−1

>0.05

NS

Faiss 2013

16:00

61 (10)

66 (7)

−5

>0.05

NS

Faiss 2013

24:00

65 (9)

71 (10)

−6

>0.05

NS

Stroke volume

       
 

Miyagawa 2010

01:05

105

107

−2

>0.05

NS

Miyagawa 2010

01:10

113

126

−13

>0.05

NS

Miyagawa 2010

01:40

116

124

−8

>0.05

NS

Cardiac output

       
 

Miyagawa 2010

01:05

15.3

14.7

 

>0.05

NS

Miyagawa 2010

01:10

17.1

18.2

 

>0.05

NS

Miyagawa 2010

01:40

19.4

20.1

 

>0.05

NS

Mean BP

       
 

Miyagawa 2010

01:05

112

107

 

>0.05

NS

Miyagawa 2010

01:10

108

107

 

>0.05

NS

Miyagawa 2010

01:40

100

99

 

>0.05

NS

BP systolic (Torr)

       
 

Faiss 2013

01:00

124 (9)

129 (13)

−5

>0.05

NS

Tucker 1983b

02:20 including 00:15 builda

−1

5

−6

 

NH > HH

Faiss 2013

08:00

124 (9)

123 (7)

1

>0.05

NS

Faiss 2013

16:00

121 (9)

118 (9)

3

>0.05

NS

Faiss 2013

24:00:00

131 (10)

129 (9)

2

>0.05

NS

  1. This table lists all the values of the measured variables that relate to the cardiovascular system.
  2. NS insignificant.
  3. aWhen the subjects entered the chamber, the environmental conditions were that of normal sea level but then were gradually made more hypoxic over the specified amount of time until the target hypoxic dose was reached.
  4. bDifference from controls.