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  1. Research

    Cardiovascular and thermal strain during 3–4 days of a metabolically demanding cold-weather military operation

    Cardiovascular (CV) and thermal responses to metabolically demanding multi-day military operations in extreme cold-weather environments are not well described. Characterization of these operations will provide...

    John W. Castellani, Marissa G. Spitz, Anthony J. Karis, Svein Martini, Andrew J. Young, Lee M. Margolis, J. Phillip Karl, Nancy E. Murphy, Xiaojiang Xu, Scott J. Montain, Jamie A. Bohn, Hilde K. Teien, Pål H. Stenberg, Yngvar Gundersen and Stefan M. Pasiakos

    Extreme Physiology & Medicine 2017 6:2

    Published on: 6 September 2017

  2. Commentary

    In conversation with…Thomas Frederic Hornbein

    Whilst attending a conference in the not too distant past, I was fortunate enough to be seated at lunch next to a very eminent octogenarian academic. Conversation ensued, and I was instantly captivated by his ...

    Ned Gilbert-Kawai

    Extreme Physiology & Medicine 2016 5:12

    Published on: 11 October 2016

  3. Methodology

    Exercise in space: the European Space Agency approach to in-flight exercise countermeasures for long-duration missions on ISS

    To counteract microgravity (µG)-induced adaptation, European Space Agency (ESA) astronauts on long-duration missions (LDMs) to the International Space Station (ISS) perform a daily physical exercise countermea...

    Nora Petersen, Patrick Jaekel, Andre Rosenberger, Tobias Weber, Jonathan Scott, Filippo Castrucci, Gunda Lambrecht, Lori Ploutz-Snyder, Volker Damann, Inessa Kozlovskaya and Joachim Mester

    Extreme Physiology & Medicine 2016 5:9

    Published on: 2 August 2016

  4. Hypothesis

    Chronic occupational exposures can influence the rate of PTSD and depressive disorders in first responders and military personnel

    First responders and military personnel experience rates of post-traumatic stress disorder (PTSD) far in excess of the general population. Although exposure to acute traumatic events plays a role in the genesi...

    Anthony Walker, Andrew McKune, Sally Ferguson, David B. Pyne and Ben Rattray

    Extreme Physiology & Medicine 2016 5:8

    Published on: 15 July 2016

  5. Review

    Moving in extreme environments: extreme loading; carriage versus distance

    This review addresses human capacity for movement in the context of extreme loading and with it the combined effects of metabolic, biomechanical and gravitational stress on the human body. This topic encompass...

    Samuel J. E. Lucas, Jørn W. Helge, Uwe H. W. Schütz, Ralph F. Goldman and James D. Cotter

    Extreme Physiology & Medicine 2016 5:6

    Published on: 22 April 2016

  6. Review

    ‘Blood doping’ from Armstrong to prehabilitation: manipulation of blood to improve performance in athletes and physiological reserve in patients

    Haemoglobin is the blood’s oxygen carrying pigment and is encapsulated in red blood corpuscles. The concentration of haemoglobin in blood is dependent on both its total mass in the circulation (tHb-mass) and t...

    James O. M. Plumb, James M. Otto and Michael P. W. Grocott

    Extreme Physiology & Medicine 2016 5:5

    Published on: 29 February 2016

  7. Research

    The effect of cold water endurance swimming on core temperature in aspiring English Channel swimmers

    The purpose of this study was to determine if cold water swimmers (CWS) developed hypothermia over a 6-h cold water endurance swim and whether body composition, stroke rate (SR) or personal characteristics cor...

    Tara Diversi, Vanessa Franks-Kardum and Mike Climstein

    Extreme Physiology & Medicine 2016 5:3

    Published on: 1 February 2016

    The Erratum to this article has been published in Extreme Physiology & Medicine 2016 5:4

  8. Research

    Caloric restriction diminishes the pressor response to static exercise

    Astronauts in space consume fewer calories and return to earth predisposed to orthostatic intolerance. The role that caloric deficit plays in the modulation of autonomic control of the cardiovascular system is...

    John P. Florian, Friedhelm J. Baisch, Martina Heer and James A. Pawelczyk

    Extreme Physiology & Medicine 2016 5:2

    Published on: 20 January 2016

  9. Commentary

    Faculty of Prehospital Care, Royal College of Surgeons Edinburgh guidance for medical provision for wilderness medicine

    To support leaders and those involved in providing medical care on expeditions in wilderness environments, the Faculty of Pre-Hospital Care (FPHC) of The Royal College of Surgeons of Edinburgh convened an expe...

    Adrian Mellor, Naomi Dodds, Raj Joshi, John Hall, Sundeep Dhillon, Sarah Hollis, Pete Davis, David Hillebrandt, Eva Howard, Matthew Wilkes, Burjor Langdana, David Lee, Nigel Hinson, Thomas Harcourt Williams, Joe Rowles and Harvey Pynn

    Extreme Physiology & Medicine 2015 4:22

    Published on: 1 December 2015

  10. Career perspective

    Career perspective: Victor A. Convertino

    This review focuses on a career of unique opportunities to participate in various areas of research related to extreme physiology and medicine. My experience as a volunteer subject in exercise experiments cond...

    Victor A. Convertino

    Extreme Physiology & Medicine 2015 4:21

    Published on: 19 November 2015

  11. Research

    Intubation after rapid sequence induction performed by non-medical personnel during space exploration missions: a simulation pilot study in a Mars analogue environment

    The question of the safety of anaesthetic procedures performed by non anaesthetists or even by non physicians has long been debated. We explore here this question in the hypothetical context of an exploration ...

    Matthieu Komorowski and Sarah Fleming

    Extreme Physiology & Medicine 2015 4:19

    Published on: 1 November 2015

  12. Research

    The increase in hydric volume is associated to contractile impairment in the calf after the world’s most extreme mountain ultra-marathon

    Studies have recently focused on the effect of running a mountain ultra-marathon (MUM) and their results show muscular inflammation, damage and force loss. However, the link between peripheral oedema and muscl...

    Damien Vitiello, Francis Degache, Jonas J. Saugy, Nicolas Place, Federico Schena and Grégoire P. Millet

    Extreme Physiology & Medicine 2015 4:18

    Published on: 20 October 2015

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